MindScreener

Prevent Alzheimer’s

Before Symptoms Appear

MindScreener uses wearable sensor technology to screen for early signs of Alzheimer’s disease, giving you the opportunity to take action sooner.
Why Screen Early?
Apply for Free Screening
  • Early Detection Technology

Rooted in Memory, Branching Into Tomorrow

Is MindScreener Right for You?

Does your memory seem less reliable lately? MindScreen may help you find clarity before it’s too late.

You May Benefit From Screening If You:

  • Are over 55 or have a family history of Alzheimer’s
  • Have noticed memory lapses or difficulty concentrating
  • Are still independent, but everyday tasks take more effort
  • Want objective clarity about your cognitive health

A Loved One May Benefit From Screening If They:

  • Forget conversations or repeat themselves frequently
  • Seem confused in familiar places or situations
  • Struggle with planning, finances, or following instructions
  • Show mood changes, withdrawal, or unusual behavior

Progression Of Alzheimer’s Symptoms (Informal)

Each stage here corresponds to a clinically recognized phase of Alzheimer’s disease. These clinical stages will be explained in more detail in the formal timeline below.

1

Asymptomatic

Brain changes being, but no noticeable symptoms

Corresponds to: Preclinical Alzheimer’s disease

2

Very Mild Decline

Minor memory lapses, often mistaken for normal aging

Corresponds to: Subjective Cognitive Decline (SCD)

3

Mild Decline

Friends and family may notice difficulties

Corresponds to: Mild Cognitive Impairment (MCI)

4

Moderate Decline

Clear symptoms, difficulty with complex tasks

Corresponds to: Mild Alzheimer’s dementia

5

Moderately Severe

Major memory gaps, assistance needed with daily activities

Corresponds to: Moderate Alzheimer’s dementia

6

Severe Decline

Constant supervision needed personality changes

Corresponds to: Severe Alzheimer’s dementia
New Alzheimer’s Disease (AD) treatments — such as Leqembi — have been approved to target the disease in its early stages, when symptoms may still appear mild or even absent. That’s why it’s crucial to understand where you stand on the Alzheimer’s progression timeline.

Understanding Alzheimer's Clinical Timeline

Preclinical Alzheimer’s Disease

This is the earliest biological phase of Alzheimer’s disease, marked by the accumulation of harmful proteins in the brain, even though no symptoms are yet observable. Traditionally, identifying this stage required expensive PET scans or invasive cerebrospinal fluid (CSF) analysis. This phase is defined using the A/T/N biomarker framework.  : 

• A+ (Amyloid): Early amyloid protein deposits.

• T- (Tau): No detectable tau-related abnormalities.

• N– (Neurodegeneration): No measurable brain shrinkage.

Understanding and identifying this stage is important, as it offers a window for early interventions before clinical symptoms appear.

MindScreener

Transitional Stage / Subtle Cognitive Decline

At this stage, subtle changes in memory or attention may begin to appear, although they often remain unnoticed in daily life. Standard cognitive tests may still fall within normal ranges. Biomarker status is now A+ and T+, indicating a progression from the previous stage where tau pathology (T) was still absent. Neurodegeneration remains minimal (N– or N±). This stage marks a critical transition in the underlying biology of Alzheimer’s disease.

MindScreener

Mild Cognitive Impairment (MCI) due to Alzheimer’s Disease

Although individuals at this stage may still function independently, measurable cognitive changes are now present. Memory lapses or difficulties with word finding often become noticeable. This stage is commonly referred to as mild cognitive impairment (MCI). The biomarker profile typically shows A+, T+, and N+, indicating ongoing progression of Alzheimer’s pathology.

MindScreener

Alzheimer's Dementia

Early Stage (Mild Alzheimer’s Dementia):

Although the person may still function independently, measurable cognitive changes are now present. This is often when memory lapses or difficulties with word finding become noticeable. The biomarker profile typically reads A+, T+, and N+, indicating progression of Alzheimer’s-related pathology.

Moderate Stage (Moderate Alzheimer’s Dementia):

At this stage, support is needed for many everyday tasks. Neurologically, further decline in brain synchronization and increased response variability may be observed, reflecting a worsening N+ status associated with neurodegeneration. Monitoring disease progression during this phase can help inform care strategies and deepen understanding of functional decline.

Late Stage (Severe Alzheimer’s Dementia):
In this stage, cognitive and physical abilities are severely affected. Although intervention options are limited, tracking residual neural function may still provide valuable information for research on late-stage care and reinforce the importance of early detection and diagnosis.

MindScreener

Alzheimer's Doesn't Start With Symptoms — So Why Should You Screen Early?

A shift in perspective. A shift in power.
Alzheimer’s develops silently for years. By the time memory loss begins, brain damage is already significant. But what if we could see it coming? What if there was a way to intervene before it’s too late?
❝ But how can I actually prevent Alzheimer's? ❞
By intervening early enough — before symptoms appear. Through:
  • Lifestyle adjustments (sleep, exercise, diet)
  • New treatments like Biogen’s Aduhelm or Leqembi
  • Monitoring brain health with tools like MindScreener
❝ But how would I know when to intervene, if there are no symptoms yet? ❞
By detecting Alzheimer’s at Stage 1 — the asymptomatic phase. Thanks to breakthroughs in low-threshold, non-invasive screening tools like MindScreener, you can start tracking your cognitive health early — from home, without medical procedures.

The Evolution of Screening Technology

Why wait for symptoms? MindScreener lets you screen your brain now — and by joining our clinical study, you’re not just protecting your future, you’re helping others do the same.

Dementia Medical Imaging Diagnostics :
From Clinic to Home

Large-Scale Clinical Imaging (Past Methods)

Traditional Alzheimer's screening relied on expensive PET and MRI scans requiring hospital visits.

Today: EEG-Based Brain Screening

In our current study, participants wear a EEG headset at a professional lab — a more accessible and non-invasive method.

Future: Portable Brain Health Tools

We're creating lightweight, user-friendly devices for at-home Alzheimer's detection and tracking, helping individuals visualize brain health and support memory activities.

Future: EEG-Based Brain Screening Accessories

Once the product is finalized, it will be possible to integrate the technology into accessories for aesthetic purposes.

The Benefits of Home Screening

Our innovative technology brings clinical-grade screening to your home, making early detection more accessible than ever.

Easy-to-Use Technology

Shape a future where brain health insights are accessible at home, anytime, through AI-driven apps.

Revolutionary Brain Monitoring

Support the development of next-generation brain mapping and cognitive tracking technologies.

Empower Yourself with Brain Training

We aim to offer future exercises that strengthen memory networks — based on your brain’s own activity.

Track Progress Over Time

Help create tools that visualize how memory and thinking skills evolve through intuitive memory maps.

Coming To A Place Near You

Making early detection accessible to everyone

1. Clinical Studies

Groundbreaking research currently in progress, validating our screening technology

2. Campaign Bus

Mobile screening lab traveling nationwide, bringing tests directly to communities

3. Local Doctors

Screenings available at participating healthcare providers in your area

4. Home Testing

User-friendly EEG headset for convenient self-screening at home

Future phases will be rolled out based on successful completion of clinical studies

Upcoming Clinical Trial Opportunities

2018–2023

Initial clinical study completed using EEG and PET imaging

Now–Q4 2025

New small-scale validation study with 40 participants — Recruitment open now

2026

Large-scale clinical trials planned

Secure your free brain health screening while spots are still open.

Register now to find out if you or a loved one qualifies for this groundbreaking clinical study. This low-effort, high-impact test is already available — but space is limited. Act early to take advantage of this unique opportunity to detect Alzheimer’s before symptoms begin.
Apply for Screening
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MindScreener

Prevent Alzheimer’s before symptoms appear

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Duigemhof Duigemhofstraat 101 3020 Herent Belgium
© 2024 MindSpeller BCI BV. All rights reserved.
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Participate in Our Alzheimer's Study

Help advance early detection by joining our study.

Before Continuing, Please Confirm You Meet These Criteria:

  • Are aged 55 or older.
  • Have a family history of Alzheimer's disease or other neurodegenerative conditions.
  • Have noticed early memory issues or mild concentration difficulties, but can still manage daily activities independently.
  • Have not been diagnosed with late-stage Alzheimer's disease or other forms of severe dementia.
  • Are interested in early detection and preventive screening before major symptoms appear.
  • Are willing to undergo non-invasive EEG testing using a comfortable, portable headset.
Understand that this screening focuses on the early biological signs of Alzheimer’s, such as the possible presence of amyloid plaques and tau proteins, even if major cognitive decline has not yet set in.
Important Notes:
We focus on individuals in the early phases of cognitive decline, not those with advanced dementia. Our goal is to support early intervention, when treatment and preventive strategies can still have the most impact.